MedWatch

Genetically modified humanized minipigs could be used in therapeutic antibody testing

Medicines based on large complicated molecules adapted for the human immune system have been difficult to test in animals before heading to clinic – now one company has bred a ”humanized minipig” for the job.

The swine breed Göttingen Minipig is one-eighth the size of a regular pig, making them easier to handle for preclinical studies | Photo: Ellegaard Göttingen Minipigs /PR

Before a new medicine can reach pharmacy shelves and hospitals, it must be thoroughly tested according to the requirements of medicinal authorities. First computer modeling and test tubes, then animals, and lastly humans.

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